看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯,血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。8 {1 _& O% r3 e
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5 ~/ v3 Q4 [, d% a% f$ U6 {Currently available feasibility data for possible combination strategies. ) ]) K3 w# c0 O. U
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& H) l) s3 h+ b9 V g, aCombination Feasibility according to preliminary data
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r6 D% f1 P+ X2 HBevacizumab + sorafenib Yes, reduced dose
0 e8 N8 F* s1 y V: oBevacizumab + sunitinib† No
. o3 B' E9 g5 Q1 aBevacizumab + temsirolimus Yes
`) P$ n9 w5 @) X* oBevacizumab + everolimus Yes 4 }: N" W9 U# Z. r' q
Sorafenib + sunitinib ? " C$ x8 s/ f+ {( x) ~( ~
Sorafenib + temsirolimus Yes, reduced dose / m; V4 Z2 \5 s3 u8 L$ s
Sorafenib + everolimus Yes, reduced dose
+ s' J; ^9 a" X& j/ ~' CSunitinib + temsirolimus† No 1 N, j: W# o i. w4 _- F
Sunitinib + everolimus ?
, X+ r9 e5 F7 R, o5 q+ l% aTemsirolimus + everolimus ? : ?) U6 E+ M5 o8 M
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, s5 `" ]! ?) U: B†Led to US FDA warning.- F8 t1 \* n+ f' `/ L2 j H
?: As yet unattempted combination.
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